Complex mammalian cell circuit design
نویسندگان
چکیده
منابع مشابه
Biomedically relevant circuit-design strategies in mammalian synthetic biology
The development and progress in synthetic biology has been remarkable. Although still in its infancy, synthetic biology has achieved much during the past decade. Improvements in genetic circuit design have increased the potential for clinical applicability of synthetic biology research. What began as simple transcriptional gene switches has rapidly developed into a variety of complex regulatory...
متن کاملThe mammalian auditory hair cell: a simple electric circuit model.
A model based on the potassium current pathway through the hair cell is used to analyze the electrical behavior of mammalian inner and outer hair cells. Without taking into account the effects of calcium it is possible to simulate experimental results concerning the shape and strength of the receptor potential and the frequency dependent ac (alternating current) and dc (direct current) componen...
متن کاملCircuit Design for Testing Standard Cell Libraries
This work presents the design methodology and the architecture of simple, efficient and easy-to-use test circuits for evaluating and validating any set of library cells (combinational and sequential logic gates), both in the design environment and for on silicon prototyping. Evaluation and validation are accomplished considering functionality, performance, power consumption and impact in operat...
متن کاملData mining approaches for modeling complex electronic circuit design activities
A printed circuit board (PCB) is an essential part of modern electronic circuits. It is made of a flat panel of insulating materials with patterned copper foils that act as electric pathways for various components such as ICs, diodes, capacitors, resistors, and coils. The size of PCBs has been shrinking over the years, while the number of components mounted on these boards has increased conside...
متن کاملA synthetic mammalian electro-genetic transcription circuit
Electric signal processing has evolved to manage rapid information transfer in neuronal networks and muscular contraction in multicellular organisms and controls the most sophisticated man-built devices. Using a synthetic biology approach to assemble electronic parts with genetic control units engineered into mammalian cells, we designed an electric power-adjustable transcription control circui...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2012
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt.2341